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This reverse transport actively pumps the newly accumulated cytosolic monoamines out of the neuron and into the synaptic cleft (Martin & Le, 2023)

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For 3D cultures, Promega recommends CellTiter-Glo 3D Cell Viability Assay, which uses an enhanced lysis buffer specifically formulated to penetrate 3D tumor spheroid structures and release ATP from cells throughout the spheroid

Compared to its sister vaccine VBI-2902, which only contains the ancestral Wuhan-Hu-1 spike, VBI-2901 generated a 2.5-fold stronger response to the ancestral strain and a ninefold stronger response against the bat coronavirus [148]

10.1016/j.tibs.2017.10.006 Trends Biochem Sci