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This shift decreased pro-inflammatory cytokines like IL-4, IL-5, and IL-13, while increasing anti-inflammatory cytokines such as IL-10 and TGF- [175]

For example, antioxidant gene therapy has been suggested as a means of overcoming the problem of poor delivery and bioavailability of antioxidant compounds at their intended sites of action (Firuzi et al., 2011)