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Data exceeding a threshold of SD = 20% for the Cramer-Rao Lower Bound estimate of the precision of the quantification were excluded from the analysis

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Therefore, we investigated the relationship between baseline PRO and contemporary clinical, radiological, and biomarker parameters in pwRMS, and, at the end of the 2-year duration of the study, the disability worsening (DW) and the occurrence of clinical or radiological inflammation