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Metformin does not replace lifestyle interventions such as a healthy diet, regular exercise, and balanced sleep

10.3390/antiox14030337 111 ValancieneE.JonuskieneI.SyrpasM.AugustinieneE.MatulisP.SimonaviciusA.et al (2020)

Arthritis Res Ther 16 , 411 (2014)

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BonekampNAJiangMMotoriEGarcia VillegasRKoolmeisterCAtanassovIet alHigh levels of TFAM repress mammalian mitochondrial DNA transcription in vivo

Recent studies demonstrate that integrating GFAP with NfL and A/tau measures significantly improves diagnostic precision and phenotypic stratification, particularly when applied within MLbased frameworks for early detection and longitudinal monitoring of disease progression [593, 594]