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[38] Kancherla V, Garn JV, Zakai NA, et al

Key muscle: Frontalis

B vitamins are water soluble vitamins and it is flushed through the body quickly and cannot be stored, and must be fed to the dog with each meal according to Wendy Volhard in the Holistic Guide for the Healthy Dog

Factors such as initial B12 levels, underlying medical conditions, certain medications, advanced age, and injection frequency can affect the absorption and utilization of B12, possibly shortening the duration of action