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Notably, as a TRX subfamily member, NRX itself supports antioxidant defense by protecting enzymes like catalase from ROS-induced oxidation, enhancing H 2 O 2 detoxification

Now I wanna pivot a little bit and talk about something else that was addressed

This cuts it off at the pass

When it is impaired, patients are more susceptible to lacunar and hemorrhagic stroke, cognitive dysfunction, and depression (116)

Strong antioxidant that protects from harsh environmental stress, helps guard against UV damage and the formation of age spots, and promotes cell growth

In order to expand the toolbox of protocols for one-pot PROTAC synthesis using building blocks with different functional groups, Krumbs group published a new library of cereblon-based PROTACs targeting BRD4 protein via amide formation after a one-pot synthesis photoinduced C(sp 2 )C(sp 3 ) coupling (yields ranging from 7 to 93%)