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2019;316:H1366h1377

In addition to the role of cytokines in immunothrombosis, macrophages have proven an important role in fibrin degradation

Importantly, Berg et al

All PK and in vivo experiments were conducted in accordance with the animal welfare procedures and were approved by the UTMDACC IACUC

The activated Nrf2-sMaf heterodimer binds to antioxidant response element (ARE) sequences in the promoter of a tandem of antioxidant genes, including heme oxygenase-1 (HMOX1), aldo-keto reductases, glutathione, and glutathione-S-transferase (Tonelli et al., 2018), to trigger their expression