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Zagorskaya 2 1 National Science and Practice Centre of Medical Assessment and Rehabilitation, Yukhnovka, 2 Minsk Regional Children's Clinical Hospital, Minsk, Belarus In the neurological department of the Minsk Regional Children's Clinical Hospital, we recently observed 2 cases of lysosomal diseasesglycolipidosis with a predominant lesion of the nervous system: GM2 gangliosisTay-Sachs disease, and cerebrosidosisKrabbe's disease