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An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitis

Finally, studies should be carried out on the potential toxicity of the drug, and more attention must be paid to possible side effects (sometimes the simplest ones, such as weight loss, increase/decrease in body temperature, etc.) that may occur when the substance is used in a given disease model

The effect of curcumin adjuvant therapy on pulmonary function and levels of interleukin-6 (IL-6) and superoxide dismutase-3 (EC-SOD3) in patients with chronic bronchial asthma

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miR-34c directly targets AR mRNA, inhibiting androgen receptor translation and compromising sperm maturation processes ( 3.5.1.2 Long non-coding RNA alterations NEAT1 undergoes upregulation following BPA exposure, influencing spermatogonial stem cell fate determination through miR-148a-3p sponging mechanisms ( 3.5.2 Protein modifications and chromatin remodeling 3.5.2.1 Post-translational modifications EED exposure promotes androgen receptor protein ubiquitination, accelerating AR degradation and reducing transcriptional activity (60)

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