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found that MSR1 binds antagonistically to fucoidan, interacts with TLR4, and triggers JNK-dependent apoptosis in ER-stressed peritoneal macrophages (112)

Clinical evidence: glycaemic control in diabetes

Live intracellular fluorescence stainings CellROX Orange Reagent, for oxidative stress detection (C10443, Invitrogen, Thermo Fisher Scientific), FerroOrange (F374, Dojindo), and BODIPY 581/591 C11 (D3861, Invitrogen, Thermo Fisher Scientific) were used according to the manufacturers instructions