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The activity of PNPO is essential for the synthesis of PLP, which is the only theoretically effective therapeutic agent, and must be taken every 6 hours

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[DOI] [PubMed] [Google Scholar] 390.Lee AZE, Tan LSY, Lim CM

You need 10-15 grams daily for optimal glutathione production, but most people consume only 3-5 grams