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Not only is there reduced production of melatonin and adrenalin in vitamin B12 deficiency, because of the requirement for methylation, there is also reduced production of CoQ10 and creatine , which are arguably the main contributing factors to the chronic fatigue seen in CFS, as these result in poor energy conversion, and gradual loss of stored muscle creatine

2 Together, these processes explain why Glutathione is regarded as the bodys master antioxidant: it can shield cells from stress and also help other antioxidant systems perform at their best

Safety aspects of the use of quercetin as a dietary supplement

Protein Assay CBB Solution (5 ) (Nacalai Tesque, Kyoto, Japan) was diluted fivefold with ion-exchanged water and dispensed in 1.5 mL portions into 2 mL tubes

Sterile process Lyophilised under ISO 8 conditions, sterile filtered