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For example, the association between NOD2 and autophagy pathway genes is weaker in East Asian populations, whereas the association between IL23R/Th17 pathway genes is more pronounced in East Asian populations [178, 202]

SRS is characterized by proportional IUGR with severe SGA at birth, relative sparing of the brain with close to normal head circumference at birth, severe feeding difficulties in infancy and childhood (which in contrast to Prader-Willi syndrome does not rebound into feeding obsession later in life), postnatal growth retardation and body asymmetry