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Interestingly, the dysfunction of the stress-regulating neuroendocrine system in elderly people along with the ageing-dependent oxidative stress are equivalent to those in humans exposed to chronic stress (99, 100)

- Qua nghin cu cho thy Glutathione l mt cht ni sinh, c kh nng chng li oxy ha t bo cc gc t do v gim sn sinh cc hc t bn trong ca c th, Glutathione l an ton v gp phn gip h thng thi c ca c th tr nn ti u

Ann Oncol 29(6):1445-1453, 2018

Two-fold concentrated stock solutions containing either 2 mM Aldrithriol-2 (Sigma-Aldrich, Darmstadt, Germany, CAS-2127-03-9, AT-2) (oxidation control), 10 mM Dithiothreitol (Sigma-Aldrich, Darmstadt, Germany, CAS-3483-12-3, DTT) (reduction control), 5 mM reduced glutathione (GSH, Sigma-Aldrich, CAS-70-18-8, pH 7.4 in 1 M HEPES), 5 mM oxidized Glutathione (GSSG, Sigma-Aldrich, CAS-27025-41-8, pH 7.4 in 1 M HEPES) or HEPES were prepared freshly

RJR, PAD, and JBB contributed equally to this work, and each has the right to list themselves first in author order on their curricula vitae