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This shortage further manifested as downregulation of beta cell identity genes and a tonic increase in endoplasmic reticulum stress markers, which resulted in diminished insulin secretion both in vitro and in vivo

J Clin Endocrinol Metab (1990) 71:14216.10.1210/jcem-71-6-1421 56 BarlierAGunzGZamoraAJMorange-RamosIFigarella-BrangerDDufourHet alPronostic and therapeutic consequences of Gs alpha mutations in somatotroph adenomas

Experimental methods Animals Domestic short haired cats (all neutered) were housed at the Pet Health and Nutrition Center (PHNC), Lewisburg, OH, USA, and all procedures were approved by the WALTHAM Animal Welfare and Ethical Review Body and the PHNC Institutional Animal Care and Use Committee

HMGB1 mediates lipopolysaccharide-induced inflammation via interacting with GPX4 in colon cancer cells

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Azar YO, Badawi GA, Zaki HF, Ibrahim SM (2022) Agmatine-mediated inhibition of NMDA receptor expression and amelioration of dyskinesia via activation of Nrf2 and suppression of HMGB1/RAGE/TLR4/MYD88/NF-B signaling cascade in rotenone lesioned rats