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10.1007/s00204-017-2148-x Arch

That breadth comes with a caveat more genes means more complexity in predicting all effects

doi: 10.1016/j.atherosclerosis.2017.05.024 104 KuwajimaMKojimaKOsakaHHamadaYJimboEWatanabeMet al

Some prefer splitting the dose between morning and evening for sustained effects

Because cortisol levels affect estrogen, progesterone, testosterone and DHEA through a shared hormonal pathway, a cortisol problem rarely stays contained to one symptom it tends to pull other hormones off course with it