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If DNA synthesis and/or methylation (epigenetic events) are altered in utero, this could affect gene expression thus impacting fetal development and that could modulate the fetal susceptibility to various diseases

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Most people get enough vitamin B12 in their diet, but some people can have a deficiency in the absorption in fact, this is particularly common in people who have had intestinal surgery, elderly people, or even people who follow a vegetarian or vegan diet, since this vitamin is only found naturally in animal-source food

Oxidative stress can damage cells and tissues, affecting fertility