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As described above, the activation of NLRP3 inflammasome leads to the maturation of IL-1 and IL-18, driving lung inflammation

Intramuscular administration of cyanocobalamin in patients with pernicious anemia and low serum levels of vitamin B12 (three to ten times lower than reference level) increases the number of CD8+ and decreases CD4/CD8 ratio back to normal [37]

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