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GSH oxidation that is independent of DHA or of chemical reactions with ROS could also occur through GRX-dependent peroxi- redoxin (PRX) or Met sulfoxide reductase (Rouhier et al., 2002

Systemic actions: They are both found in several tissues, as well as in circulation, where they modulate metabolism, oxidative stress, cell survival, and inflammation

To examine whether the chemical conjugation of MK-801 to GLP-1 mitigates the adverse hyperthermic and hyperlocomotive effects of MK-801, mice were subjected to body temperature measurements and open-field behavioural tests after chronic and acute drug administration, respectively

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[0229] Embodiment 222: A method of expanding a population of genetically engineered T cells in a mammal diagnosed with cancer, said method comprising administering to said mammal administering to said mammal a T cell genetically modified to express a chimeric antigen receptor (CAR) according to any one of embodiments 201- 205, wherein the administered genetically engineered T cell produces a population of progeny T cells in the human

van Elburg 1993)