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While potential side effects may include temporary redness at injection sites and mild headaches, this balanced perspective emphasizes the importance of considering both the benefits and the safety of the treatment

Recent studies have shown that deletion of mitochondrial pyruvate carriers in cancer cells disrupts this balance, reducing GSH synthesis and negatively impacting cell proliferation 168

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For example, the deletion of compo-nents of the glutathione detoxication system such as glutathione peroxidase (Mirochnitchenko et al ., 1999) and glutathione transferase-pi (GST-pi) (Henderson et al ., 2000) both afforded partial protection against paracetamol hepatotoxicity

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