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Mechanisms underlying the hepatotoxicity of nonsteroidal anti-inflammatory drugs

The B-017 sequence, GRKKRRQRRRPQWVELHFFN, consisted of 12 amino acids from the HIV-1 protein transduction domain (PTD) 4859 at the N-terminus and eight amino acids 1320 derived from BNIP3 containing the substitution S19F at the C terminus

132 Intraperitoneal administration of the Citrus sinensis essential oil in alloxan-induced diabetic rats significantly reduces fasting blood glucose and hepatic glucose and increases hepatic glycogen at 110 mg/kg body weight

Transforming growth factor (TGF)-, expressed by trophoblasts, was found to inhibit trophoblast invasion and proliferation through reducing MMP-9 and stimulating MMP inhibitors like tissue inhibitor of metalloproteinase (TIMP) (46)

In atherosclerosis, arterial regions with turbulent blood flow, such as branch points, are particularly prone to lesions due to low shear stress and endothelial damage