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To confirm that no other DNA damage-responsive PIKK family member phosphorylates CD98HC S103, at least in response to H 2 O 2 , we used inhibitors of DNA-PKcs and ATR (AZD7648 and AZD6738, respectively) and observed no impairment (Fig

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Considering the T = 4 icosahedral symmetry of CHIKV, however, VH and VL regions of the Fab molecules are either in close proximity (within 3 ) or overlapping with Mxra8 D1 on the adjacent spike when we tried to align the Fab-bound structure with the Mxra8-bound one

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(PubMed) Potgieter M, Pretorius E, Pepper MS

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