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Neuron 74, 691705

It was noted that ERR inverse agonist XCT 790 has been shown to clear -synuclein aggregates in an autophagy-dependent, mTOR-independent manner, offering potential neuroprotective effects in Parkinsons disease models by enhancing autophagosome biogenesis [139]

First, c-Met inhibitors only affect high-expression c-Met patients with HCC

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Some findings suggest potential cardiovascular benefits, particularly in certain populations, though more research is needed

The metabolic and mitochondrial disturbances have a two-way relationship with amyloid-beta and tau pathology, neuroinflammation, and oxidative stress, thus creating a self-sustaining cycle of neurodegeneration