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Furthermore, in an in vivo study, MMPs were shown to recruit CD8+ T cells through the production of CXCL16 while simultaneously inhibiting the expression of Reg3a, E-cadherin, and ZO-1

aureus )a striking increase in horizontal gene transfer efficiency linked directly to NP presence (Ding et al., 2016)

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Some scholars also believe that, in women affected by thyroid autoimmunity, the thyroid may have insufficient TH release in the early stages of pregnancy, and their increased miscarriage rate may be due to TH deficiency rather than a systemic overreaction of the immune system (Abalovich et al., 2007)