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The absence of tissue growth effects also means AOD-9604 avoids many common side effects of growth hormone therapy including joint pain and swelling from connective tissue proliferation, carpal tunnel syndrome from tissue expansion, edema and fluid retention from protein synthesis and sodium retention, and concerns about growth-promoting effects in individuals with tumor history

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They both aim to influence fat metabolism, but their pathways are distinct, almost orthogonal

For example, eating fortified foods can help

PA remains largely under-researched in clinical practice, contributing to gaps in diagnosis, management, and patient care