When PTU was given to hypothyroidism control experimental rats, it probably inhibited the synthesis of protein which in turn decreased the thyroxine-binding globulin (Reference Kochman, Jakubczyk and Bargiel3,Reference Seven, Seymen and Hatemi21Reference Sharsher, Ahmed and Metwally24,Reference Lewicki, Lesniak and Bertrandt42)
Alpina Oil , Beta-Carotene, Lutein, Ascorbic Acid, Soy Lecithin, Monoglycerides, Potassium Citrate, Calcium Carbonate, Potassium Chloride, Carrageenan, Ferrous Sulfate, Magnesium Chloride, Choline Chloride, Choline Bitartrate, Taurine, Inositol, Calcium Phosphate, Zinc Sulfate, Potassium Phosphate, d-Alpha-Tocopheryl Acetate, Niacinamide, Calcium Pantothenate, L-Carnitine, Vitamin A Palmitate, Copper Sulfate, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, Salt, Potassium Iodide, Potassium Hydroxide, and Nucleotides (Adenosine 5'-Monophosphate, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate)
H., Kundrat, L
Lastly, we performed protein thermal shift assays on the GDAP1TM T157P mutant and found that its thermal transition was very similar to that of wild-type, demonstrating that the loss of 4HNE binding is not the result of an overall loss of stability or folding ( Figure 6G )
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Biochemistry 54 , 49364951 (2015)
