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Deficits in hippocampal neurogenesis in obesity-dependent and -independent type-2 diabetes mellitus mouse models

This was accomplished by promoting the production of proteins with antioxidant activity, such as HO-1, SOD2, SOD3, and Prdx-1, which is reliant on Akt activation [176]

MDA, a reactive aldehyde, belongs to a class of reactive electrophile species that induce toxic stress in cells and form covalent protein adducts known as advanced lipoxidation end products, similar to advanced glycation end products

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By Type 9.3.1.2.2

Furthermore, the dual inhibition of glutaminase and CPT1 has been shown to reduce the proliferation and migration of CB-839-resistant cells in comparison to the inhibition of individual enzymes