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Cell 1 : 543551 Rueffli AA, Smyth MJ and Johnstone RW (2000) HMBA induces activation of caspase-independent cell death pathway to overcome P-glycoprotein-mediated multidrug resistance

In addition, CXCL12 can also induce the expression of CTGF in human lung fibroblasts by activating the MEKK1/JNK signaling pathway (Lin et al., 2018)

It has less muscle wasting, much better safety profile, lower side effect profile, but people drop substantial amounts of body fat

One important reason is that, currently, there is no effective clinical treatment for HS [4]

2017;11:BC136

Irizarry-Caro RA, McDaniel MM, Overcast GR, Jain VG, Troutman TD, Pasare C