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Description

Transduction of the ghrelin gene into the heart rescues Cardiomyocytes from ROS accumulation and apoptosis, Restores heart function after myocardial infarction in an autophagy manner (C).Desacyl ghrelin also reduce ROS production, lowers tissue inflammation and reinforces insulin stimulated glucose uptake in skeletal muscle in an autophagy dependent manner[26]

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Continued efforts are also needed at a global level to challenge existing perceptions around SPIGFD, and identify solutions that promote equitable access to appropriate care