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Programmed cell death associated with autophagy Autophagy, derived from the Greek words auto meaning self and phagy meaning to eat, is a highly conserved cellular process that is essential for maintaining cellular health and homeostasis (Ohsumi, 2014)

10.1073/pnas.71.4.1056 11 BatemanA

Core Mechanisms Recap: NNMT Inhibition: Prevents NAD depletion, supporting energy production and metabolic flexibility

GoldsteinJSilbersteinSDSaperJRElkindAHSmithTRGallagherRMet al

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Chitose Oneyama (Aichi Cancer Center Research Institute) for providing PANC-1 cells, Dr Eiji Morita (Hirosaki University) for CD63 expressing plasmid, and the Life Science Collaboration Center (LiSCo) at Nara Institute of Science and Technology for their technical support, and all members of the laboratory for their technical assistance and helpful discussions