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Methods: ALG-000184-201 is a multi-part, multi-center, double-blind, randomized, placebo-controlled Phase 1b study (NCT04536337) evaluating the safety, pharmacokinetic, and antiviral activity profiles of oral daily dosing with ALG-000184 in heathy volunteers (7 d) and subjects with chronic hepatitis B (48 weeks)

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Patients often report reduced pain, better energy, improved mood, and sharper mental clarity

doi: 10.3389/fnagi.2025.1495769 Received 13 September 2024 Accepted 28 March 2025 Published 09 May 2025 Volume 17 - 2025 Edited by Ramesh Kandimalla, Indian Institute of Chemical Technology (CSIR), India Reviewed by Chunchen Xiang, Capital Medical University, China Bruno piljak, University of Zagreb, Croatia Updates Copyright 2025 Li, Zhang, Yu, Xue and Hu

It bypasses the skin barrier problem entirely