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GHK-Cu is a copper binding peptide studied in laboratory settings for its role in cellular signalling, collagen related pathway analysis, and tissue response research

Liontos, M., Anastasiou, I., Bamias, A

Failure of MK-801, to attenuate kainate-induced cell damage under excitotoxic conditions has led to the conclusion that OLCs do not express NMDARs (Yoshioka et al., 1995) and that excitotoxicity in oligodendrocytes is mediated through non-NMDA glutamatergic receptors (Yoshioka et al., 1995, 2000

Combining them with a peptide that also increases nitric oxide production could theoretically produce excessive vasodilation, leading to dangerous blood pressure drops

Subjective human perception of improvement likely lags behind histological tissue changes

Thats when supplementation becomes essential