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When bromelain interacts with the mucosal lining of the gut, it helps to modulate the local immune response and reduce localized inflammation

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Several types of selective autophagy, such as ferritinophagy, clockophagy, lipophagy, and mitophagy, promote ferroptotic cell death through degradation of the iron-storing protein ferritin, the core circadian clock protein aryl hydrocarbon receptor nuclear translocator-like (ARNTL, also known as BMAL1), LDs, and mitochondria, respectively (Liu et al., 2019

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