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A 2014 study published in Osteoarthritis and Cartilage found that AOD 9064 combined with hyaluronan significantly improved cartilage repair in animal models

Both the Dosage and Administration and Warnings and Precautions sections now include recommendations to obtain baseline liver function tests (LFTs) within 3 months prior to initiation and to monitor for signs and symptoms of hepatic injury during treatment

An important role of excipients is to tailor delivery profiles, with ingredients used to alter a formulations viscosity, pH, or theoretical charge at pH 7.4 to control release profile

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Choudhary AK, Pretorius E

However, side effects can occur, and long-term safety data are limited