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Methylation affects DNA repair, detoxification, and brain functionall areas where children with autism may need extra help

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Comment: One commenter supported the Agency's discontinuation of the gradual reduction policy but recommended that we reinstate such a policy in the future to avoid dramatic and unexpected negative reductions in the target PCR

MOTS-c does not produce a dose-dependent linear response where more injections yield proportionally better results

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This analysis estimated variance across facilities and measured facility-specific standard errors to determine the extent to which variance in facility scores can be attributed to variance in actual performance