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Your specific protocol should always be determined by your supervising physician

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Stimulation of cells expressing both c-MET and EGFR with EGF resulted in phosphorylation of c-MET, and stimulation with ligands for both receptors resulted in synergistic activation of downstream modulators, indicating mutual activation of these two pathways [Puri and Salgia, 2008]

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Inserting the given values into the equation, This result makes sense because the [A ]/[HA] ratio is between 1 and 10, so the pH of the buffer must be between the p K a (3.75) and p K a + 1, or 4.75

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