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In the absence of oxygen, pyruvate produced during glycolysis is converted to lactate by lactate dehydrogenase (LDH) (34)

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Successful therapeutic peptides in this category often show high selectivity for their target enzymes while maintaining appropriate pharmacokinetic properties for clinical use

(3) from arcade 2 to the next arcade (arcade 3) to the last arcade inside the ligations (or the previous ligation) (2-3, Figures 2, 5-8, 21 and 22)