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The most serious but rare complication is metformin-associated lactic acidosis (MALA), typically occurring in the setting of renal impairment and mechanistically linked to mitochondrial complex I inhibition (Zhou et al., 2001)

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PMID 17606868

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Doctronic.ai uses advanced AI technology to provide personalized medical advice based on your dosage, medical history, and current medications

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ChengZJiangXPansuriaMFangPMaiJMallilankaramanKet alHyperhomocysteinemia and hyperglycemia induce and potentiate endothelial dysfunction via mu-calpain activation

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Produced in the liver endogenously, glutathione is an extremely important antioxidant for the body and iits ability to reduce free-radical damage

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AJP Ren Physiol [Internet], 302 (2012), pp

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