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In addition, DNA methylation influences the expression of T cell cytokines interleukin (IL)-2, IFN-gamma, IL-4 and IL-13, 35 36 and the Treg-canonical transcription factor, FOXP3

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iCC model: To develop an iCC model, six-eight-week old mice were injected through hydrodynamic tail vein injection with different combinations of tumor oncogene plasmids and were characterized 6-8 weeks post injection

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