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Deregulated expression of insulin-like growth factor 1 in prostate epithelium leads to neoplasia in transgenic mice

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By the end of the study, mean daily insulin dose decreased from baseline by 3.8 U ( 11.4%) in participants receiving insulin glargine plus tirzepatide 15 mg but increased by 25.1 U (75%) in those receiving insulin glargine plus placebo [12]