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Topical sodium nitrite for chronic leg ulcers in patients with sickle cell anaemia: a phase 1 dose-finding safety and tolerability trial

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Am J Transl Res 12:26272639 Chughlay MF, Kramer N, Spearman CW, Werfalli M, Cohen K (2016) N-acetylcysteine for non-paracetamol drug-induced liver injury: a systematic review

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Furthermore, from 2010 to 2021, the 'age-standardized disability-adjusted life-years' for MDD increased by 16.4% [4]

108,109 The decrease in mitochondrial membrane potential induces PINK1 aggregation and autophosphorylation on the outer mitochondrial membrane, which recruits Parkin to initiate the PINK1-Parkin mitophagy pathway to remove damaged mitochondria