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Mario Thevis, German Sport University Cologne Research Title: Effect of alternative routes of drug administration on metabolic profiles in doping controls exposure vs

Specifically, the protein ankyrin repeat and SOCS box protein 1 (ASB1) (a substrate-recognition subunit of an E3 ubiquitin ligase complex) binds to SQOR and mediates K48-linked ubiquitination of SQOR, targeting it for proteasomal degradation

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Redox Biol 38:101797 Yan J, Ralston MM, Meng X, Bongiovanni KD, Jones AL, Benndorf R (2013) Glutathione reductase is essential for host defense against bacterial infection

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IN THE FIRST HEAD-TO-HEAD STUDY OF BIOLOGICS IN UC ENTYVIO: SUPERIOR to Humira (adalimumab) In clinical remission at Week 52 in the overall population 2,3 * VARSITY primary end point (overall population): ENTYVIO IV 31% (n=383) vs 23% (n=386) with Humira ( P =0.006