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Acknowledgements This work was supported by the National Research Foundation of Korea [NRF] grant funded by the Korea government (MSIP) (Grant Number MRC.2008-0062275)

PLoS One 10 (7), e0131464

Pain, itching, or swelling around the injection site may occur but should fade within 24 hours

Possible Side Effects Ipamorelin is generally well-tolerated in preclinical and limited human research studies, with a favorable safety profile compared to earlier growth hormone releasing peptides

Although benefits of mRNA CTNS delivery are mutation-independent, efficient delivery to kidney cells and expression of the mRNA remain difficult [155, 157]