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doi: 10.1186/1475-2875-7-S1-S8 56 World Health Organization (2016)

While the amount of homocysteine in the blood is regulated by several nutrients, including folate and choline, conditions that cause damage to the liver like nonalcoholic steatohepatitis (NASH) may also affect homocysteine metabolism (36)

Funding This work was financially supported by a grant from the Agriculture Funding Consortium (2018F019R)

This phenotype was absent from the catalase/peroxidase-proficient parent, showing that it depends upon H 2 O 2 stress (Figure 8C)

it supports natural metabolic processes rather than providing immediate alertness

Clinical features of children with GDH-HI include persistent mild hyperammonemia, hypoglycemia after fasting or high protein (especially leucine) diets, and neuroglycopenic symptoms including seizures