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Very rare but more serious side effects include irregular heartbeats/ palpitations or in extremely rare cases can cause an allergic reaction (anaphylaxis) but I have an EpiPen at hand to treat you immediately should this extremely rare occurrence happen.

The larger the volume of a shot, the more pressure effect/tissue stretching effect that may occur and in a sensitive child cause a feeling of discomfort

In accordance with this inhibition of vasorelaxation by reactive oxygen species, moderate hyperhomocysteinemia-induced endothelial dysfunction in mice heterozygous for a CBS defect was associated recently with an increased oxidant stress (Eberhardt et al, 2000)

Supplementing with oral B12 may work for some people

2 Your liver does most of the work breaking down alcohol

B6 also supports the creation of neurotransmitters like serotonin and dopamine, which help regulate mood, sleep and overall energy