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Sickle cell disease is caused by an inherited mutation in the globin gene that creates hemoglobin S, an abnormal form of hemoglobin which is prone to polymerization with deoxygenation resulting in sickling of red blood cells, hemolytic anemia, vascular occlusion of small vessels causing ischemic tissue and organ injury and recurrent painful crises

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Peptide structure: Small and stable for experimental use in vitro and in vivo

PMID: 40338179 Glutathione oxidized disodium purchased from MedChemExpress

AOD 9604 showed only 2.6 kilograms of weight loss in its best trial result and failed to demonstrate significant weight loss in six clinical trials overall

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