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Additionally, an overabundance of the 16-OH metabolite characterizes her breakdown in Phase 1

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For instance, high concentrations of methionine, S-adenosylmethionine and homocysteine favor the transsulfuration over the remethylation in cells, thereby reducing the excessive accumulation of homocysteine and reducing the occurrence of severe hyperhomocysteinemia 17

( After consideration of public comments as discussed in section V.C

(Lykov et al., 2020) implanted Wistar rats BMSCs with/without erythropoietin (EPO) into the IDD mouse model

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