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Acetyl-CoA can then be oxidized to produce energy (ATP) in the citric acid cycle

power = 80% Randomization Intervention allocation was done by using a random number list and eligible patients were randomly allocated to trial groups in a ratio of 1:1

Clinically, in patients with renal failure, acute kidney injury, dialysis and other pathological states of renal function deterioration, renal reabsorption function is impaired, resulting in a significantly lower serum free carnitine concentration than that in healthy people [255], and the metabolic profile of acylcarnitine also changes significantly [256]

Here, we suggest that in these disorders, peripheral serotonin levels are low, and elevating them to normal range with L-carnitine is accompanied with reduced fatigue

Diary cards were provided to participants on days 1, 7, 14, and 21, onto which participants were instructed to record their temperature, adverse events (AEs), medication, and supplementation

On one hand, many studies have supported a cardioprotective role for L-carnitine [8,9,10]