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WNT genes also enhance cell migration by increasing various matrix metalloproteinase genes that degrade the ECM, allowing more efficient cell migration through the matrix [104]

Consequently, a strategy that focuses on breaking the seizureinflammationcircuit instability loop through targeted modulation of long-range neural circuits and projection pathways is essential for advancing epilepsy treatment

R.MetselaarB.GreenoughM.BushA

"Activity-dependent dendritic arborization mediated by CaM-kinase I activation and enhanced CREB -dependent transcription of Wnt-2." Neuron 50(6): 897-909