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Discussion This review covers the importance of maintaining NAD + levels for cellular homeostasis and mitochondrial maintenance, as well as evaluating established and novel NAD + boosting strategies from simple supplementation of precursors to modulation of enzymes by drugs

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Furthermore, the inflammatory milieu in TMJ OA and KOA may also contribute to differential effects of ferroptosis

Tips for managing side effects Always start with the low dose to minimize the risk of side effects

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